Immunomodulatory Effects of Macrolide Antibiotics – Part 1: Biological Mechanisms
نویسندگان
چکیده
منابع مشابه
Immunomodulatory effects of macrolide antibiotics - part 1: biological mechanisms.
Macrolide antibiotics are well known for their antibacterial and anti-inflammatory properties. This article provides an overview of the biological mechanisms through which macrolides exert this 'double effect'. Their antibacterial effect consists of the inhibition of bacterial protein synthesis, impaired bacterial biofilm synthesis, and the attenuation of other bacterial virulence factors. Apar...
متن کاملImmunomodulatory Effects of Macrolide Antibiotics - Part 1: Biological Mechanisms
Macrolide antibiotics are well known for their antibacterial and anti-inflammatory properties. This article provides an overview of the biological mechanisms through which macrolides exert this ‘double effect’. Their antibacterial effect consists of the inhibition of bacterial protein synthesis, impaired bacterial biofilm synthesis, and the attenuation of other bacterial virulence factors. Apar...
متن کاملImmunomodulatory Effects of Macrolide Antibiotics - Part 1: Biological Mechanisms
Macrolide antibiotics are well known for their antibacterial and anti-inflammatory properties. This article provides an overview of the biological mechanisms through which macrolides exert this ‘double effect’. Their antibacterial effect consists of the inhibition of bacterial protein synthesis, impaired bacterial biofilm synthesis, and the attenuation of other bacterial virulence factors. Apar...
متن کاملImmunomodulatory effects of macrolide antibiotics - part 2: advantages and disadvantages of long-term, low-dose macrolide therapy.
The available evidence for long-term, low-dose treatment with 14- and 15-membered ring macrolides in non-cystic fibrosis (CF) bronchiectasis, COPD, chronic sinusitis, and asthma is reviewed with special attention to possible adverse effects and the emergence of resistance during long-term macrolide treatment. Macrolide maintenance therapy has been proven to be of benefit in diffuse panbronchiol...
متن کاملImmunomodulatory Effects of Macrolide Antibiotics - Part 2: Advantages and Disadvantages of Long-Term, Low-Dose Macrolide Therapy
The available evidence for long-term, low-dose treatment with 14and 15-membered ring macrolides in non-cystic fibrosis (CF) bronchiectasis, COPD, chronic sinusitis, and asthma is reviewed with special attention to possible adverse effects and the emergence of resistance during long-term macrolide treatment. Macrolide maintenance therapy has been proven to be of benefit in diffuse panbronchiolit...
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ژورنال
عنوان ژورنال: Respiration
سال: 2011
ISSN: 1423-0356,0025-7931
DOI: 10.1159/000320319